INGREDIENTS

Hyaluronic acid, hidrosoluble collagen,  1 key ingredient and 3 more biomimetic peptides:

COSMECEUTIC AND THERAPEUTIC DIRECTIONS

This product is a very efficient solution  at attenuating expression wrinkles,  at getting  a global strong anti-aging effect and mainly at promoting remarkable lifting effect.

It shows high levels of boosting collagen and elastin synthesis which facilitates the improvement of the epidermis tissue and as regards better skin vitality and luminosity.

*These are advisable therapeutic uses, but the ingredients of products may allow a physician to apply them under professional criteria, may find the product optimal to treat other aesthetic issues.

 

CLINICAL DATA 

Pharmacology 

 Pharmacology of the formula active compounds which promotes lifting effect:

Hyaluronic Acid:

• Manteins the right and optimal level of skin tissue hydration, as a result the skin keeps its normal biochemical surrounding that reinforce the collagen and elastin synthesis.

Hydrosoluble collagen:

• Due to its skin structural protein inherent characteristic, it promotes the smoothing and firmness of the skin.
• It has got  great volumizing attribute.

Argireline, Hexapeptide-8:

• Argireline acetate temporarily limits the overproduction and release of neurotransmitters that initiate and control the intensity of facial muscle contractions.
•  At a 10% concentration, Hexapeptide-8 has been shown to reduce the depth of wrinkles up to 30% after 30 days of trial use.
• Argireline is a peptide (hexapeptide-8) that inhibits SNARE complex formation and catecholamine release, resulting in the reduction of the degree of existing facial wrinkles.

• Repeated muscle contraction leads to the formation of expression wrinkles that are an unpleasant sign of aging. Thus, modulation of muscle contraction leads to muscle relaxation which avoids the formation of expression lines. A more relaxed face shows a younger side, a tighter skin and much fewer wrinkles, furrows and creases.
• This molecule has proven in vivo to diminish wrinkles caused by facial expression by inactivating the formation of the agrin/MuSK complex, which is essential for muscle contraction.

• Reduces and prevents lines and wrinkles by actively generating new skin cells.
• Enhances skin tone that brimming with vitality and energy.
• Minimize scars on skin by forming new skin cell.
• Up-regulation of cell growth and migration, cell survival and extracellular matrix expression.
• Cell Proliferation with Keratinocyte and Fibroblast Cells.
• Increased  fibroblasts and  keratinocytes proliferation in dose-dependent manner.
• I has showed positive regulation of Hyaluronic acid and Fibronectin expression. Increased expression of hyaluronic acid (3 folds) and Elastin (1.3 fold) was observed in dose-dependent manner  in fibroblast cells.
• This molecule increases cell survival of keratinocytes cell line by its anti apoptosis attribute, also enhances the attachment of cell by means of EGF, growing epidermic factor regulation.

• Potent skin fibroblast cell proliferation agent, the peptide increases fribroblast cell proliferation in a dose dependent manner.
• The fibroblast cell morphology also changes and indicates a positive lifting effect.
• It shows remarkable positive regulation on collagen and fibronectin expression by fibroblast and keratinocyte cells.
• Also cell attachment improves which helps to promote lifting effect.

Posology and way of administration 

They should be done by the supervision of physician  or a registered nurse and they will apply the best technique available in each case.

The product is developed sterile, preservative free and pyrogen free to be used on several aesthetic techniques, IPL, roller and other invasive or non invasive procedures.